Also, these signatures are not limited to just diseases, but extends further to an individual’s response to certain drugs/therapy, susceptibility to environmental factors such as toxins, so on and so forth.For example, it can discern how well you can handle stress or how well you can digest a specific diet or even how well you can cope with depression. More importantly, these genetic variations, defining a character or disease, can be inherited by your siblings, making it even more critical to know your genetics. Because of this, genomic approaches have gained huge clinical importance in the past decade, identifying and understanding unique genetic signatures, further allowing us to move towards personalized medicine.
The most critical challenge that needs immediate response in the analysis of genome sequencing data is to arrive at exact information desired by a clinician or a researcher, to diagnose or to treat a disease that you might be predisposed to.
Given this background, our efforts are directed towards identifying comprehensive sequence dataset for an individual and detailed evaluation of all genetic variations in an individual, which might be predisposing you to varying degrees of disease risk, assisting you in understanding your "Genome Rich Signature™" involving better health. To this end we have developed a robust pipeline called "AGIS"
and also an evidence based database LRB-Vries
that feeds into the pipeline to make accurate variant annotation”